Effect of salbutamol in infants with wheezy bronchitis.
نویسنده
چکیده
Using the technique of whole body plethysmography, lung mechanics were measured in a group of infants with wheezy bronchitis. Compared with a group of normal infants previously studied, airway resistance and thoracic gas volume were found to be raised. Nebulized salbutamol was then administered and measurements were repeated when it was found that there was no objective improvement. It is concluded that salbutamol may not be an effective form of treatment of wheezy bronchitis in young infants and the reasons for this are discussed.
منابع مشابه
Effect of bronchodilators on respiratory resisance in infants and young children with bronchiolitis and wheezy bronchitis.
Rutter, N., Milner, A. D., and Hiller, E. J. (1975). Archives of Disease in Childhood, 50, 719. Effect of bronchodilators on respiratory resistance in infants and young children with bronchiolitis and wheezy bronchitis. Respiratory resistance was measured using a forced oscillation technique in 16 infants and young children with bronchiolitis and wheezy bronchitis. Measurements were made before...
متن کاملEffect of bronchodilators on respiratory resistance in infants and young children with bronchiolitis and wheezy bronchitis
Acute obstructive airways disease in infancy and early childhood, diagnosed as bronchiolitis or wheezy bronchitis, is a common reason for hospital admission and is occasionally fatal. Phelan, Williams, and Freeman (1968) and Phelan and Williams (1969a) have shown that the major physiological abnormality is an increase in airways resistance, similar to that found in older children and adults wit...
متن کاملAirway responsiveness following wheezy bronchitis in infants.
The study was undertaken to assess the airway function and its response to carbachol and salbutamol in infants recovering from wheezy bronchitis. In 82 children aged 3-33 mths, free from wheeze at the time of testing, and in 14 healthy infants, airway resistance (Raw) and thoracic gas volume (TGV) were measured using a body plethysmograph. Specific airway resistance (sRaw = Raw x TGV) was calcu...
متن کاملInhaled salbutamol for wheezy infants: a randomised controlled trial.
BACKGROUND Salbutamol is frequently used as a bronchodilator for infants who wheeze. Many single dose studies have questioned its effectiveness. AIMS To investigate the response of wheezy infants to salbutamol over an extended time period in order to elucidate either symptomatic relief or a protective effect. METHODS Eighty infants under 1 year, with persistent or recurrent wheeze and a per...
متن کاملDose - response relationships and time course of the response to systemic beta adrenoreceptor agonists in infants with bronchopulmonary disease RICHARD
The lung function response to three doses of salbutamol 0 075 mg/kg given at 10 minute intervals by gastric tube was studied in 31 infants aged 2-22 months with bronchopulmonary disease (eight after the respiratory distress syndrome, 15 with wheezy bronchitis, and eight with cystic fibrosis). Lung function was measured by whole body plethysmography. Seven of 31 infants had normal lung function ...
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عنوان ژورنال:
- Archives of disease in childhood
دوره 50 7 شماره
صفحات -
تاریخ انتشار 1975